Qianrong Guo

Qianrong Guo

PhD student at Imperial College London

Imperial College London

Biography

Hello! I’m a first-year PhD student at the Bioengineering department in Imperial College London, under the guidance of Dr. Pedro Ballester (about our group). Prior to beginning my PhD, I completed my Masters at the University of Edinburgh, where I collaborated with Dr. Diego Oyarzún on machine learning applications for Phenotypic Drug Discovery. I received my Bachelor’s degree from China University of Geosciences. My current research focuses on leveraging Artificial Intelligence for Phenotypic Virtual Screening, with the goal of making noteworthy advancements in the field of drug discovery. I have a strong interest in developing innovative computational approaches that can expedite the identification of potential drug candidates for various diseases.

Interests
  • Artificial Intelligence
  • Drug Discovery
Education
  • PhD in Artificial Intelligence for Phenotypic Virtual Screening, 2023

    Imperial College London

  • Msc in Bioinformatics, 2021

    The University of Edinburgh

  • BSc in Biology, 2017

    China University of Geosciences

Experience

 
 
 
 
 
WuXi Biologics
Development Intern
September 2022 – December 2022 Shanghai

Data Technology and Analysis Department - Data Technology AI Team

Responsibilities:

  • Graph-based and language model development for Protein-protein Interaction (PPI) prediction and antibiotic discovery
 
 
 
 
 
The University of Edinburgh
Research Assistant
April 2022 – August 2022 Edinburgh

Responsibilities:

  • Conducted research on deep learning techniques in phenotypic drug discovery against glioblastoma cells.

  • Developed and optimized a graph neural network for feature extraction, combining information from RDkit and features extracted from a large pre-trained language model (ChemBERTa).

  • Improved model architecture and evaluation metrics, particularly for handling imbalanced data.

 
 
 
 
 
China University of Geosciences
Research Assistant
April 2020 – June 2021 Wuhan

Effects of red phosphorus on metabolism of microorganisms. Supervised by Dr. Liang Feng.

Responsibilities:

  • Investigated the effects of red phosphorus on the metabolism of microorganisms.

  • Utilized Gradient Boosting Tree and Random Forest algorithms to predict the optimal concentration of different types of red phosphorus using transcriptomics data and visible light wavelength.

  • Conducted data cleaning, analysis, and visualization using Python.

 
 
 
 
 
China University of Geosciences
Research Assistant
March 2019 – July 2019 Wuhan

Neosinocalamus growth prediction using image data

Responsibilities:

  • Analyzed the growth and development of Neosinocalamus affinis using image data.

  • Collected and processed leaves from Neosinocalamus affinis.

  • Applied K-means clustering to analyze the correlation between the size, number, and positions of phytoliths and the growth of Neosinocalamus affinis.

  • Identified the connection between the cells’ structure and components at the molecular level and the growth of Neosinocalamus affinis.

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